Clinical implications of predominant polarity and the polarity index in bipolar disorder: a naturalistic study.

@article{Popovic2014ClinicalIO,
  title={Clinical implications of predominant polarity and the polarity index in bipolar disorder: a naturalistic study.},
  author={Dina Popovic and C Torrent and Jos{\'e} Manuel Goikolea and N{\'u}ria Cruz and J Sanchez-Moreno and Ana Gonzalez-Pinto and Eduard Vieta},
  journal={Acta psychiatrica Scandinavica},
  year={2014},
  volume={129 5},
  pages={366-74}
}
OBJECTIVE Predominant polarity (PP) is an important variable in maintenance treatment of bipolar disorder (BD). This study aimed at determining the role of polarity index (PI), a metric indicating antimanic versus antidepressive prophylactic potential of drugs, in clinical decision-making. METHOD Two hundred and fifty-seven of 604 (43%) of patients with BD-I or II fulfilled criteria for manic (MPP) or depressive PP (DPP). The PI, representing the ratio of number needed to treat (NNT) for… CONTINUE READING