Clinical implications of germline mutations in breast cancer: TP53

@inproceedings{Schon2017ClinicalIO,
  title={Clinical implications of germline mutations in breast cancer: TP53},
  author={Katherine Schon and Marc Tischkowitz},
  booktitle={Breast Cancer Research and Treatment},
  year={2017}
}
This review describes the prevalence of germline TP53 mutations, the risk of breast cancer and other cancers in mutation carriers and management implications for women with breast cancer and unaffected women. Literature review of English language papers available through PubMed. Women who carry germline mutations in the TP53 gene have a very high risk of breast cancer of up to 85% by age 60 years. Most of these breast cancers are early onset with a median age at diagnosis of 34 years… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
1 Extracted Citations
41 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 41 references

Similar Papers

Loading similar papers…