Clinical implications of discordance between low-density lipoprotein cholesterol and particle number.

@article{Otvos2011ClinicalIO,
  title={Clinical implications of discordance between low-density lipoprotein cholesterol and particle number.},
  author={James D. Otvos and S Jimera Mora and Irina Shalaurova and Philip Greenland and Rachel H. Mackey and David C Goff},
  journal={Journal of clinical lipidology},
  year={2011},
  volume={5 2},
  pages={
          105-13
        }
}
BACKGROUND The amount of cholesterol per low-density lipoprotein (LDL) particle is variable and related in part to particle size, with smaller particles carrying less cholesterol. This variability causes concentrations of LDL cholesterol (LDL-C) and LDL particles (LDL-P) to be discordant in many individuals. METHODS LDL-P measured by nuclear magnetic resonance spectroscopy, calculated LDL-C, and carotid intima-media thickness (IMT) were assessed at baseline in the Multi-Ethnic Study of… CONTINUE READING
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