Clinical implications for statin pleiotropy.

  title={Clinical implications for statin pleiotropy.},
  author={James K. Liao},
  journal={Current opinion in lipidology},
  volume={16 6},
PURPOSE OF REVIEW Atherosclerosis is a multi-factorial condition involving dyslipidemia that can result in cardiovascular disease. Statins are potent inhibitors of cholesterol biosynthesis, and in clinical trials, statins have been shown to be beneficial in the primary and secondary prevention of coronary heart disease. However, the overall benefits observed with statins appear to occur much earlier and to be greater than what might be expected from changes in lipid levels alone, suggesting… CONTINUE READING


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