Clinical impact of selective serotonin reuptake inhibitors therapy with bleeding risks

  title={Clinical impact of selective serotonin reuptake inhibitors therapy with bleeding risks},
  author={M. S. Turner and D. B. May and R. Arthur and G. Xiong},
  journal={Journal of Internal Medicine},
  • M. S. Turner, D. B. May, +1 author G. Xiong
  • Published 2007
  • Medicine
  • Journal of Internal Medicine
  • The selective serotonin reuptake inhibitors (SSRIs) are extensively used for the treatment of multiple psychiatric conditions. In vitro and ex vivo data with these agents indicate they may have varying degrees of antiplatelet activity via multiple receptors. Reports of bleeding in patients receiving SSRIs appeared soon after their introduction. A review of the literature suggests SSRI therapy may increase the risk of bleeding especially with concomitant aspirin or nonsteroidal anti‐inflammatory… CONTINUE READING
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