Clinical impact of mesorectal extranodal cancer tissue in rectal cancer: detailed pathological assessment using whole-mount sections.

@article{Shimada2010ClinicalIO,
  title={Clinical impact of mesorectal extranodal cancer tissue in rectal cancer: detailed pathological assessment using whole-mount sections.},
  author={Yoshifumi Shimada and Yasumasa Takii},
  journal={Diseases of the colon and rectum},
  year={2010},
  volume={53 5},
  pages={771-8}
}
PURPOSE Mesorectal cancer deposits showing no histological evidence of lymph node structure (extranodal cancer tissue) are a common feature in rectal cancer. However, optimal categorization of extranodal cancer tissue using TNM grading is not yet established. We reviewed extranodal cancer tissue in detail using whole-mount sections to clarify its clinical impact. METHODS This retrospective study involved 214 consecutive patients with stage I-III rectal cancer. After fixation, the whole tumor… CONTINUE READING

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