Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations.

@article{Walsh2013ClinicalIO,
  title={Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations.},
  author={Edward E. Walsh and Jae Hyun Shin and Ann R Falsey},
  journal={The Journal of infectious diseases},
  year={2013},
  volume={208 10},
  pages={1634-42}
}
BACKGROUND The incidence and clinical impact of coronavirus (CoV) infection in elderly persons and those with underlying cardiopulmonary disease over a long duration is not well described. We determined the incidence and clinical impact of 229E and OC43 CoV in this population during 4 consecutive winters, and compared illnesses to influenza A, respiratory syncytial virus, and human metapneumovirus. METHODS CoV 229E and OC43 were detected by reverse transcription polymerase chain reaction and… CONTINUE READING
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