Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis?

@article{Opal1999ClinicalGS,
  title={Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis?},
  author={Steven M. Opal and Jonathan Cohen},
  journal={Critical care medicine},
  year={1999},
  volume={27 8},
  pages={1608-16}
}
OBJECTIVE To review the basic differences between gram-positive and gram-negative sepsis and to assess the effect of these differences on current and future therapeutic strategies for sepsis. DESIGN Literature review of the past 30 yrs of laboratory and clinical reports that analyze the microbial aspects of sepsis and the immunologic response to systemic infection. RESULTS The increasing prevalence of sepsis from gram-positive bacterial pathogens necessitates reevaluation of many of the… CONTINUE READING

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