Clinical features of major depressive disorder in adolescents and their relatives: impact on familial aggregation, implications for phenotype definition, and specificity of transmission.

@article{Klein2002ClinicalFO,
  title={Clinical features of major depressive disorder in adolescents and their relatives: impact on familial aggregation, implications for phenotype definition, and specificity of transmission.},
  author={Daniel N. Klein and Peter M. Lewinsohn and Paul Rohde and John R Seeley and Chris Durbin},
  journal={Journal of abnormal psychology},
  year={2002},
  volume={111 1},
  pages={98-106}
}
Three questions were addressed using family study data from a community sample: (a) Which clinical features of major depressive disorder (MDD) in adolescents are associated with elevated rates of MDD in relatives? (b) Which features of MDD in relatives distinguish family members of depressed adolescents from relatives of adolescents without mood disorders… CONTINUE READING