Clinical features of interleukin 10 receptor gene mutations in children with very early-onset inflammatory bowel disease.


OBJECTIVES In the present study, we studied a cohort of patients with very early onset inflammatory bowel disease (IBD) to determine the frequency of mutations in the interleukin 10 (IL10) receptor genes as a cause of early-onset IBD. METHODS Sanger sequencing was performed to determine the presence of IL10 and/or IL10 receptor mutations in 17 patients… (More)
DOI: 10.1097/MPG.0000000000000621


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