Clinical features of hypersensitivity reactions to oxaliplatin among Chinese patients with colorectal cancer


Oxaliplatin is a third­generation platinum antineoplastic agent. The 2­amino­cyclohexane­platinum DNA that oxaliplatin forms is more hydrophobic than that formed by cisplatin and carboplatin. 1 The renal toxicity of oxaliplatin is milder than cisplatin, while its bone marrow suppression action is weaker than carboplatin. Nervous system toxicity is the main… (More)