Clinical features of adult patients with secondary hemophagocytic lymphohistiocytosis from causes other than lymphoma: an analysis of treatment outcome and prognostic factors

@article{Park2011ClinicalFO,
  title={Clinical features of adult patients with secondary hemophagocytic lymphohistiocytosis from causes other than lymphoma: an analysis of treatment outcome and prognostic factors},
  author={Han-Seung Park and Dae-Young Kim and Jae-Hong Lee and Jung-Hee Lee and Sung-Doo Kim and Young-Hun Park and Jae Seok Lee and Bo Youn Kim and Mijin Jeon and Y S Kang and Y S Lee and Miee Seol and Yeon-Joo Lee and Young-Suk Lim and Seongsoo Jang and Chan Park and Hyun-sook Chi and K A Lee},
  journal={Annals of Hematology},
  year={2011},
  volume={91},
  pages={897-904}
}
Although hemophagocytic syndrome (HS) featuring secondary hemophagocytic lymphohistiocytosis (HLH) has a grave prognosis, little is known about the natural course of the disease. Patients who showed the clinical features of HLH as well as tissue-proven hemophagocytosis when seen at Asan Medical Center between 1999 and 2010 were included in this analysis. Patients with proven lymphoma were excluded. The median age of our 23 study patients was 49 years. Epstein–Barr virus was suspected to have… CONTINUE READING
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