Clinical features of TTR-FAP in Portugal.

@article{Conceio2012ClinicalFO,
  title={Clinical features of TTR-FAP in Portugal.},
  author={Isabel Maria Conceiç{\~a}o},
  journal={Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis},
  year={2012},
  volume={19 Suppl 1},
  pages={
          71-2
        }
}
Familial amyloid polyneuropathy (FAP) is an autosomal dominant disorder characterized by the extracellular deposition of transthyretin (TTR) fibrils in several tissues, particularly in the peripheral nervous system. The largest focus of the disease is in Portugal where the age of disease onset shows a wide range (17-78 years), with 80% of cases developing symptoms before age 40. The characteristic fiber length-dependent sensory-motor and autonomic neuropathy are the neurological hallmark of TTR… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 18 REFERENCES

Role of heart rate variability in the assessment of autonomic dysfunction in type I familial amyloidotic polyneuropathy

  • MJ Correia, CA Coutinho, +4 authors E Oliveira
  • Folia Cardiol ;12:459–462
  • 2005
1 Excerpt

Anticipation in familial amyloid neuropathy type I (FAP-I): the possible role of a genetic modifier

  • A Sousa, T Coelho, J Barros, J. Sequeiros
  • J Neurol ;S1:48
  • 1995
1 Excerpt

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