Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)

  title={Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)},
  author={P. Kennedy},
  journal={The Lancet Neurology},
  • P. Kennedy
  • Published 2013
  • Biology, Medicine
  • The Lancet Neurology
  • Human African trypanosomiasis, or sleeping sickness, is caused by infection with parasites of the genus Trypanosoma, transmitted by the tsetse fly. The disease has two forms, Trypanosoma brucei (T b) rhodesiense and T b gambiense; and is almost always fatal if untreated. Despite a recent reduction in the number of reported cases, patients with African trypanosomiasis continue to present major challenges to clinicians. Because treatment for CNS-stage disease can be very toxic, diagnostic staging… CONTINUE READING
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