Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.

@article{Smith1998ClinicalFO,
  title={Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.},
  author={I. R. L. Smith and Ibrahim Taşkintuna and Firas M. Rahhal and Henry C. Powell and Everett Ai and Arthur J. Mueller and Stephen A Spector and William R. Freeman},
  journal={Archives of ophthalmology},
  year={1998},
  volume={116 2},
  pages={
          178-85
        }
}
  • I. R. L. Smith, Ibrahim Taşkintuna, +5 authors William R. Freeman
  • Published in Archives of ophthalmology 1998
  • Medicine
  • OBJECTIVES To determine the incidence of clinical resistance to intraocular cidofovir injection for treatment of acquired immunodeficiency syndrome (AIDS)-related cytomegalovirus (CMV) retinitis, and to identify virologic features associated with cidofovir treatment failure. PATIENTS AND METHODS Clinical resistance to intravitreal cidofovir was examined in 64 patients with CMV retinitis who received at least 1 injection of 20 pg of cidofovir. Histopathologic examination, culture, and… CONTINUE READING

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