Clinical factors that influence response to treatment strategies in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study.

@article{Curtis2005ClinicalFT,
  title={Clinical factors that influence response to treatment strategies in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study.},
  author={Anne B Curtis and Bernard J. Gersh and Scott D Corley and John P Dimarco and Michael J. Domanski and Nancy V Geller and Harry L. Greene and Joyce C Kellen and Mary C Mickel and Joy Dalquist Nelson and Yves D Rosenberg and Eleanor P Schron and Lynn R Shemanski and Albert L. Waldo and D. George Wyse},
  journal={American heart journal},
  year={2005},
  volume={149 4},
  pages={645-9}
}
BACKGROUND The AFFIRM Study was a randomized multicenter comparison of 2 treatment strategies, rate-control versus rhythm-control, in high-risk patients with atrial fibrillation (AF). The primary outcome of the trial showed no overall difference in survival between strategies. However, there may be important patient subgroups for which there are identifiable differences in outcome with 1 of the 2 strategies. METHODS AND RESULTS Subgroups that were prespecified for analysis from the main… CONTINUE READING

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