Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient.

@article{Ramphal1996ClinicalEW,
  title={Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient.},
  author={Reuben Ramphal and Rasim A Gucalp and Coleman Rotstein and Michael Cimino and D Oblon},
  journal={The American journal of medicine},
  year={1996},
  volume={100 6A},
  pages={83S-89S}
}
Choice of antibiotic therapy for the management of infection in the neutropenic patient continues to challenge the clinician. The shift toward gram-positive organisms and the continuing need to provide gram-negative coverage demands the use of an agent or agents that provide coverage for the spectrum of potential infecting organisms. Cefepime is an extended-spectrum fourth-generation cephalosporin that has good activity against gram-positive and gram-negative organisms; in addition, it resists… CONTINUE READING