Clinical experience with penicillin skin testing in a large inner-city STD clinic.

@article{Gadde1993ClinicalEW,
  title={Clinical experience with penicillin skin testing in a large inner-city STD clinic.},
  author={J Gadde and Mathew Spence and B Wheeler and Newton Franklin Adkinson},
  journal={JAMA},
  year={1993},
  volume={270 20},
  pages={2456-63}
}
OBJECTIVE To establish (1) the prevalence of positive penicillin skin tests among outpatients with well-defined but variable history of penicillin allergy and (2) the reproducibility, safety, and negative predictive value of skin testing with benzylpenicilloyl polylysine (PPL) and a minor-determinant mixture (MDM). DESIGN Serial consenting outpatients with current indications for penicillin therapy were skin-tested in duplicate with PPL and MDM. Subjects with negative skin tests (93% of those… CONTINUE READING
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