Clinical experience with intravenous valproate as first-line treatment of status epilepticus and seizure clusters in selected populations.

OBJECTIVE The aim of this study was to evaluate the efficacy and safety of intravenous valproate (i.v. VPA) as first-line treatment of status epilepticus (SE) and seizure clusters in selected patient populations. METHODS We enrolled 23 patients (11 females and 12 males; mean age: 61 years) with SE who received i.v. VPA as first-line therapy (25 mg/kg in… CONTINUE READING