Clinical experience with cyanoacrylate tissue adhesive

  title={Clinical experience with cyanoacrylate tissue adhesive},
  author={M. Moschos and Dimitrios Droutsas and P. Boussalis and George Tsioulias},
  journal={Documenta Ophthalmologica},
In this paper 385 cases treated with cyanoacrylate tissue adhesive during the years 1980–1995 are studied. The indications, outcomes and complications of cyanoacrylate adhesive are investigated and the results are analysed.It is encouraging that except for three cases of ocular hypotony and two cases of microbial infection no other complications occurred. Even in desperate cases with corneal perforation greater than 3 mm and ocular infection, enucleation was avoided. The early use of a bandage… 
Scleral Patch Graft Augmented Cyanoacrylate Tissue Adhesive for Treatment of Moderate-Sized Noninfectious Corneal Perforations (3.5–4.5 mm)
Scleral patch graft augmented CTA technique is a successful alternative treatment method to emergent penetrating keratoplasty for corneal perforations that measure 3.5 to 4.5 mm.
Tenons Patch Graft in the Management of Large Corneal Perforations
This procedure makes use of easily available autologous Tenons tissue in patients with corneal perforations too large to be managed with cyanoacrylate glue alone, to preserve eyeball morphology.
Use of cyanoacrylate adhesive in the surgical management of feline corneal sequestrum: 16 cases (2011-2018).
Cyanoacrylate adhesive is an effective and safe alternative to grafting procedures in cats undergoing lamellar keratectomy for treatment of corneal sequestrum and benefits of this approach include decreased anesthesia time, lower procedure costs, and short duration of postoperative treatment.
Outcomes of Cyanoacrylate Tissue Adhesive Application in Corneal Thinning and Perforation
CTA application was moderately effective in stabilizing corneal perforation and thinning in the very short-term and maintenance of globe integrity after glue application decreases with time and the need for surgical intervention remains high.
Household Cyanoacrylate is an Efficient and Safe Adhesive for Urgent Repair of Cerebrospinal Leaks
Cyanoacrylate adhesive seems to be an efficient and safe alternative for the prevention of low-pressure CSF leaks and is followed up for no CSF leakage, infection, or neurological problems.
Allergic reaction to Dermabond in gynaecologic surgery
A 63-year-old female presented on post-operative day 7 status post total laparoscopic hysterectomy and bilateral salpingo-oophorectomy with sudden onset erythema and pruritus around all four port site incisions with suspicion of an allergic reaction to Dermabond.
Ocular surface sealants and adhesives.


Clinical experience with N-butyl cyanoacrylate (Nexacryl) tissue adhesive.
Cyanoacrylate glue in the treatment of corneal ulcerations.
  • S. Golubović, A. Parunović
  • Medicine
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • 1990
This method of treatment was applied in 30 patients with corneal melting in dry eye associated with rheumatoid arthritis, trophic postherpetic ulcerations of the cornea, chemicalCorneal burns, neurotrophic corneals ulceration and Mooren's ulcer.
The use of adhesive for the closure of corneal perforations. Report of two cases.
The surgical adhesive n-heptyl 2-cyanoacrylate was used successfully to seal corneal perforations in two patients, and acted as a tamponade allowing the normal healing process to occur beneath it, and elimination of suturing in diseased tissue.
Sodium hyaluronate and tissue adhesive in treating corneal perforations.
Toxicity of alkyl 2-cyanoacrylates. II. Bacterial growth.
A family of adhesives, the alkyl 2-cyanoacrylates, have been receiving increasing attention from surgeons in the hope of improving various surgical procedures, and interest evolved by the introduction of the methyl monomer.
Any tissue adhesive to be used within the body must be sterile and not be capable of acting as a vehicle.
Experimental Sutureless Ocular Surgery
Infectious keratitis and cyanoacrylate adhesive.