Clinical experience with and side-effects of tacrine hydrochloride in Alzheimer's disease: a pilot study.

Pharmacological manipulation of central cholinergic neurotransmission may prove beneficial in the treatment of Alzheimer's disease (AD). Tacrine hydrochloride is a central anticholinesterase which has been said to improve intellectual function in patients with AD. We report here our clinical experience with this drug in eight patients with AD, diagnosed… CONTINUE READING