Clinical experience with an implantable, intracardiac, continuous flow circulatory support device: physiologic implications and their relationship to patient selection.

@article{Frazier2004ClinicalEW,
  title={Clinical experience with an implantable, intracardiac, continuous flow circulatory support device: physiologic implications and their relationship to patient selection.},
  author={O. Howard Frazier and Timothy J Myers and Stephen Westaby and Igor D. Gregoric},
  journal={The Annals of thoracic surgery},
  year={2004},
  volume={77 1},
  pages={133-42}
}
BACKGROUND We have been investigating continuous-flow circulatory support devices for 20 years. Unlike pulsatile assist devices, continuous-flow pumps have a simplified pumping mechanism and they do not require compliance chambers or valves. In the 1980s, clinical experience with the Hemopump proved a high-speed, intravascular, continuous-flow pump could safely augment the circulation. Subsequently, a decade of animal experiments with a larger, longer-term continuous-flow pump (the Jarvik 2000… CONTINUE READING

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