Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial.

@article{Watanabe1997ClinicalEW,
  title={Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial.},
  author={F D Watanabe and Claudy J-P Mullon and Winston R. Hewitt and Nikolaos Arkadopoulos and E Kahaku and Susumu Eguchi and Ted Khalili and W S Arnaout and Christopher R Shackleton and Jacek Rozga and Beth Solomon and Achilles A. Demetriou},
  journal={Annals of surgery},
  year={1997},
  volume={225 5},
  pages={484-91; discussion 491-4}
}
OBJECTIVE The purpose of this study was to develop a bioartificial liver (BAL) to treat patients with severe liver failure until they can be either transplanted or recover spontaneously. SUMMARY BACKGROUND DATA Severe acute liver failure is associated with high mortality. Liver transplantation has emerged as an effective therapy for patients who did not respond to standard management. However, because of the donor organ shortage and urgent need for transplantation, many patients die before… CONTINUE READING

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