Clinical evidence on the efficacy and tolerability of a topical medical device containing benzoylperoxide 4%, retinol 0.5%, mandelic acid 1% and lactobionic acid 1% in the treatment of mild facial acne: an open label pilot study

@article{Garofalo2019ClinicalEO,
  title={Clinical evidence on the efficacy and tolerability of a topical medical device containing benzoylperoxide 4\%, retinol 0.5\%, mandelic acid 1\% and lactobionic acid 1\% in the treatment of mild facial acne: an open label pilot study},
  author={V. Garofalo and M. Cannizzaro and S. Mazzilli and L. Bianchi and E. Campione},
  journal={Clinical, Cosmetic and Investigational Dermatology},
  year={2019},
  volume={12},
  pages={363 - 369}
}
Background: Acne is a debilitating disorder that requires proper treatment depending on the clinical manifestations and pathogenetic factors, among which hyper-keratinization, seborrhea and bacterial proliferation. Combining active ingredients targeting the different mediators of acne pathogenesis may yield optimal outcomes. Purpose: The purpose of this study was to evaluate the clinical effectiveness, safety and tolerability of a new topical medical device in cream containing benzoylperoxide 4… Expand

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