Clinical evaluation of the NS1 antigen-capture ELISA for early diagnosis of dengue virus infection in Brazil.

@article{CastroJorge2010ClinicalEO,
  title={Clinical evaluation of the NS1 antigen-capture ELISA for early diagnosis of dengue virus infection in Brazil.},
  author={Luiza Antunes de Castro-Jorge and Paula Renata Lima Machado and Camila A F{\'a}vero and Marcos de Carvalho Borges and Luzia M R Passos and Rosana Moreira de Oliveira and Benedito Ant{\^o}nio Lopes da Fonseca},
  journal={Journal of medical virology},
  year={2010},
  volume={82 8},
  pages={1400-5}
}
The fact that the diagnosis of infection with dengue virus is usually made by detecting IgM antibodies during the convalescent phase of the disease interferes with disease management and, consequently, with reducing mortality rates. This study evaluated the sensitivity and specificity of detection of NS1 in samples of patients suspected of acute dengue virus infection in Brazil. The results were used to institute treatment and the sensitivity and specificity of detection of NS1 were compared to… CONTINUE READING
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