Clinical evaluation of systemic and local immune responses in cancer: time for integration

@article{Gutkin2013ClinicalEO,
  title={Clinical evaluation of systemic and local immune responses in cancer: time for integration},
  author={Dmitriy W. Gutkin and Michael R. Shurin},
  journal={Cancer Immunology, Immunotherapy},
  year={2013},
  volume={63},
  pages={45-57}
}
The immune system has a dual role in cancer development and progression. On the one hand, it can eradicate emerging malignant cells, but on the other hand, it can actively promote growth of malignant cells, their invasive capacities and their ability to metastasize. Immune cells with predominantly anti-tumor functionality include cells of the innate immune system, such as natural killer cells, and cells of adaptive immunity, such as conventional dendritic cells and cytotoxic T lymphocytes… CONTINUE READING

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References

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Showing 1-10 of 132 references

An immunohistochemical study of CD1a and CD83-positive infiltrating dendritic cell density in cervical neoplasia.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists • 2007
View 11 Excerpts
Highly Influenced

Jekyll or Hyde

JE Talmadge, M Donkor, tumors Scholar E Inflammatory cell infiltration of
Cancer Metastasis Rev 26(3–4):373–400 54 Cancer Immunol Immunother • 2014
View 1 Excerpt

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