Clinical evaluation of a (1,3)-beta-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients.

Abstract

(1,3)-beta-d-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.

DOI: 10.1128/CVI.00276-09

Cite this paper

@article{Bono2009ClinicalEO, title={Clinical evaluation of a (1,3)-beta-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients.}, author={Valerio del Bono and Alessandra Mularoni and Elisa Furfaro and Emanuele Delfino and Lorenzo Rosasco and Franca Miletich and Claudio Viscoli}, journal={Clinical and vaccine immunology : CVI}, year={2009}, volume={16 10}, pages={1524-6} }