Clinical evaluation of PRMT1 gene expression in breast cancer

  title={Clinical evaluation of PRMT1 gene expression in breast cancer},
  author={Konstantina Mathioudaki and Andreas Scorilas and Alexandros G Ardavanis and Peggy Lymberi and Evangelos Tsiambas and Marina Devetzi and Aikaterini Apostolaki and Maroulio Litsa Talieri},
  journal={Tumor Biology},
Methylation of arginine residues has been implicated in many cellular activities like mRNA splicing, transcription regulation, signal transduction and protein–protein interactions. Protein arginine methyltransferases are the enzymes responsible for this modification in living cells. The most commonly used methyltransferase in man is protein arginine methyltransferase 1 (PRMT1). Since methylation processes appear to interfere in the emergence of several diseases, including cancer, we… CONTINUE READING