• Medicine
  • Published in Neuro endocrinology letters 2004

Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

@article{Russo2004ClinicalED,
  title={Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?},
  author={Ethan B. Russo},
  journal={Neuro endocrinology letters},
  year={2004},
  volume={25 1-2},
  pages={
          31-9
        }
}
OBJECTIVES This study examines the concept of clinical endocannabinoid deficiency (CECD), and the prospect that it could underlie the pathophysiology of migraine, fibromyalgia, irritable bowel syndrome, and other functional conditions alleviated by clinical cannabis. METHODS Available literature was reviewed, and literature searches pursued via the National Library of Medicine database and other resources. RESULTS Migraine has numerous relationships to endocannabinoid function. Anandamide… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 122 REFERENCES

Pharmacology of cannabidiol at serotonin receptors

B Hall, A Burnett, +3 authors E Russo
  • Western Pharmacology Society,
  • 2004

Cannabis and cannabinoids as medicines

BA Whittle, GW Guy, P. Robson
  • 2003