Clinical efficacy of the transdermal tulobuterol patch in patients with chronic obstructive pulmonary disease: a comparison with slow-release theophylline.


BACKGROUND There is insufficient evidence for the efficacy of a transdermal tulobuterol patch (TP), although combination therapy with bronchodilators is recommended for chronic obstructive pulmonary disease (COPD). OBJECTIVE A randomized, controlled crossover study was conducted to evaluate the clinical efficacy and safety of the TP in 16 patients with… (More)


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