Clinical efficacy of subgingivally delivered 0.5% controlled release azithromycin gel in the management of chronic periodontitis.

@article{Tyagi2011ClinicalEO,
  title={Clinical efficacy of subgingivally delivered 0.5% controlled release azithromycin gel in the management of chronic periodontitis.},
  author={Prashant Tyagi and Shubhra Vaish and Vidya Dodwad},
  journal={Indian journal of medical sciences},
  year={2011},
  volume={65 6},
  pages={223-30}
}
BACKGROUND Recent developments suggest that the local delivery of antimicrobials into periodontal pockets can improve periodontal health. Azithromycin (AZM) has a wide antimicrobial spectrum of action toward anaerobic bacteria as well as Gram-negative bacilli. It is effective against periodontal pathogens such as Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Therefore, this study was undertaken to investigate the clinical effectiveness of AZM at 0.5% concentration in an… CONTINUE READING

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