Corpus ID: 14744402

Clinical efficacy of selamectin for the control of fleas on dogs and cats.

@article{Kwochka2000ClinicalEO,
  title={Clinical efficacy of selamectin for the control of fleas on dogs and cats.},
  author={Kenneth W. Kwochka and Duygu Yaman Gram and Gail A. Kunkle and Karin Muth Beale and Candace A. Sousa and Andr{\'e}a Cannon and Jon D Plant},
  journal={Veterinary therapeutics : research in applied veterinary medicine},
  year={2000},
  volume={1 4},
  pages={
          252-60
        }
}
  • K. Kwochka, D. Gram, +4 authors J. Plant
  • Published 2000
  • Medicine
  • Veterinary therapeutics : research in applied veterinary medicine
The topical endectocide selamectin (Revolution, Pfizer Animal Health) was evaluated in seven veterinary dermatology specialty clinics for its ability to control fleas on 75 dogs and 46 cats from single- and multiple-animal households. All animals were treated on days 0, 30, and 60 with a minimum unit dose of 6 mg/kg of selamectin(h) applied to the skin in a single spot at the base of the neck in front of the scapulae. The product was applied according to label instructions, and the use of other… Expand

References

SHOWING 1-10 OF 17 REFERENCES
The efficacy of selamectin in the treatment of naturally acquired infestations of sarcoptes scabiei on dogs.
TLDR
Topical administration to the skin in a single spot of a single unit dose of selamectin, or of two unit doses given 1 month apart, was highly effective against naturally acquired infestations of S. scabiei in dogs, reducing mite counts by >93% (single dose) and 100% ( two doses). Expand
The efficacy of selamectin in the treatment of naturally acquired aural infestations of otodectes cynotis on dogs and cats.
TLDR
Selamectin administered topically at a minimum dosage of 6mgkg(-1) was safe and 100% effective against naturally acquired aural infestations of O. cynotis in dogs and cats after a single dose or after two doses administered 1 month apart. Expand
Evaluation of the effects of selamectin against adult and immature stages of fleas (Ctenocephalides felis felis) on dogs and cats.
TLDR
Selamectin was shown to be highly effective in the treatment and control of flea infestations (C. felis) on dogs and cats. Expand
Efficacy of selamectin against experimentally induced tick (Rhipicephalus sanguineus and Dermacentor variabilis) infestations on dogs.
TLDR
Seven controlled studies demonstrated that selamectin, administered topically to the skin in a single spot at a minimum dosage of 6mgkg(-1) at monthly intervals, was effective in the control of experimentally induced R. sanguineus and D. variabilis infestations on dogs. Expand
Efficacy of selamectin against experimentally induced and naturally acquired infections of Toxocara cati and Ancylostoma tubaeforme in cats.
TLDR
A single topical unit dosage providing a minimum dosage of 6mgkg(-1) selamectin was highly effective in the treatment of naturally acquired and experimentally induced infections of T. cati and A. tubaeforme in cats. Expand
The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity.
TLDR
It is concluded that avermectins and milbemycins mediate their nematocidal effects on C. elegans via an interaction with a common receptor molecule, glutamate-gated chloride channels. Expand
Evaluation of the ovicidal and larvacidal effects of selamectin against fleas (Ctenocephalides felis) on dogs
  • Proc Am Assoc Vet Parasitol. Salt Lake City,
  • 2000
Efficacy of selamectin against fleas (Ctenocephalides felis) on dogs and cats bathed 24 hours after treatment
  • Proc Am Assoc Vet Parasitol
  • 1999
Efficacy of selamectin, fipronil, imidacloprid and lufenuron against Ctenocephalides felis on cats
  • Proc Am Assoc Vet Parasitol
  • 1999
Efficacy of selamectin, fipronil, imidacloprid and lufenuron/milbemycin against Ctenocephalides felis on dogs
  • Proc Am Assoc Vet Parasitol
  • 1999
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