Clinical efficacy and tolerability of linezolid in pediatric patients: a systematic review.

BACKGROUND Linezolid is marketed for the treatment of severe, vancomycin-resistant infections with gram-positive bacteria in adults. Most information regarding the pharmacokinetic profile, efficacy, and tolerability of linezolid is derived from adult studies. OBJECTIVE The aim of this review was to summarize evidence regarding the use of linezolid in… (More)