Clinical effects of actarit in rheumatoid arthritis: improvement of early disease activity mediated by reduction of serum concentrations of nitric oxide.

@article{Nakamura2000ClinicalEO,
  title={Clinical effects of actarit in rheumatoid arthritis: improvement of early disease activity mediated by reduction of serum concentrations of nitric oxide.},
  author={Hironobu Nakamura and Yukitaka Ueki and Sohko Sakito and Ken-ichi Matsumoto and Michiko Yano and S. Miyake and Yoshihiro Tominaga and Kenji Eguchi},
  journal={Clinical and experimental rheumatology},
  year={2000},
  volume={18 4},
  pages={
          445-50
        }
}
OBJECTIVE We previously reported the presence of high serum concentrations of nitric oxide (NO) in patients with rheumatoid arthritis (RA). In this study we evaluated the effect of actarit on patients with early and advanced stages of RA and the relationship between RA activity and serum NO levels. METHODS Thirty-seven RA patients who were undergoing care at Sasebo Chuo Hospital were entered into the study. Patients were divided into two groups based on the severity of their disease: group I… CONTINUE READING

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