Clinical effectiveness and quality of life with ranitidine vs placebo in gastroesophageal reflux disease patients: a clinical experience network (CEN) study.

@article{Rush1995ClinicalEA,
  title={Clinical effectiveness and quality of life with ranitidine vs placebo in gastroesophageal reflux disease patients: a clinical experience network (CEN) study.},
  author={Davia Rush and W J Stelmach and Terri L Young and Leonard Kirchdoerfer and J A Scott-Lennox and H E Holverson and Seymour M. Sabesin and Tom Nicholas},
  journal={The Journal of family practice},
  year={1995},
  volume={41 2},
  pages={126-36}
}
BACKGROUND Gastroesophageal reflux disease (GERD), often characterized as heartburn, is a highly common presenting complaint to family physicians. This study is the first large, prospective, nationwide family practice outpatient evaluation of the effectiveness of the histamine (H2)-receptor antagonist ranitidine as medical therapy for this disorder. METHODS This randomized, double-blind, placebo-controlled, parallel group, 6-week study was designed to evaluate the effect of ranitidine on… CONTINUE READING

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