Clinical disorders of extracellular calcium-sensing and the molecular biology of the calcium-sensing receptor.

@article{Pearce2002ClinicalDO,
  title={Clinical disorders of extracellular calcium-sensing and the molecular biology of the calcium-sensing receptor.},
  author={Simon H. S. Pearce},
  journal={Annals of medicine},
  year={2002},
  volume={34 3},
  pages={201-6}
}
The calcium-sensing receptor is a G protein-coupled receptor that has a key role in extracellular calcium homeostasis, regulating the secretion of parathyroid hormone and the reabsorption of urinary calcium appropriate to the prevailing calcaemic environment. Molecular abnormalities of the calcium-sensing receptor are responsible for three clinical disorders, familial benign hypocalciuric hypercalcaemia, neonatal severe hyperparathyroidism and autosomal dominant hypocalcaemia with… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…