Clinical correlations and prognosis based on hyaluronic acid serum levels in patients with progressive systemic sclerosis.

@article{Lvesque1991ClinicalCA,
  title={Clinical correlations and prognosis based on hyaluronic acid serum levels in patients with progressive systemic sclerosis.},
  author={Herv{\'e} L{\'e}vesque and Nathalie Baudot and Bertrand Delpech and Michel Vayssairat and A. Gancel and P H Lauret and Hubert Courtois},
  journal={The British journal of dermatology},
  year={1991},
  volume={124 5},
  pages={423-8}
}
The serum levels of hyaluronic acid (sHA) were measured using an affinoimmunoenzymatic assay in patients with distal (n = 16) and proximal (n = 15) progressive systemic sclerosis (PSS) and in 31 controls. The severity of PSS was evaluated using a standardized organ-involvement score. The mean sHA was significantly higher in the patients with PSS than in controls (mean +/- SD:80 +/- 43.4 micrograms/l vs. 42.3 +/- 19.1 micrograms/l, P less than 0.001). sHA was significantly higher in patients… CONTINUE READING