Clinical correlates of cerebral water diffusion in Wilson disease.

  title={Clinical correlates of cerebral water diffusion in Wilson disease.},
  author={Pascal Favrole and Hugues Chabriat and Jean Pierre Guichard and France Woimant},
  volume={66 3},
OBJECTIVE To investigate the course of diffusion changes in Wilson disease (WD) and to evaluate their clinical and radiologic correlates. METHODS MRI with fluid-attenuated inversion recovery (FLAIR) and diffusion weighted images (DWI) were performed in 13 symptomatic patients with WD who had typical neurologic manifestations of the disease (sWD patients) and in 5 presymptomatic patients (psWD patients). Follow-up clinical and MRI data were obtained in 12/13 patients with sWD. Ten subjects… CONTINUE READING
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