Clinical correlates of JAK2V617F allele burden in essential thrombocythemia.

@article{Kittur2007ClinicalCO,
  title={Clinical correlates of JAK2V617F allele burden in essential thrombocythemia.},
  author={Jaya Kittur and Ryan A. Knudson and Terra L. Lasho and Christy M. Finke and Naseema Gangat and Alexandra P. Wolanskyj and C Y Li and Wenting Wu and Rhett P. Ketterling and Animesh Pardanani and Ayalew Tefferi},
  journal={Cancer},
  year={2007},
  volume={109 11},
  pages={2279-84}
}
BACKGROUND JAK2V617F occurs in approximately 50% of patients with essential thrombocythemia (ET). Qualitative studies of mutation analysis have previously reported an association between JAK2V617F and advanced age, higher hemoglobin level, higher leukocyte count, and lower platelet count. A possible association with thrombotic complication has also been considered. METHODS Allele-specific, quantitative polymerase chain reaction (PCR) analysis for JAK2V617F was performed in 176 patients with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 66 extracted citations

Similar Papers

Loading similar papers…