Clinical correlates and substrate specificities of antibodies exhibiting neutrophil nuclear reactivity--a methodological study.

@article{Cour1995ClinicalCA,
  title={Clinical correlates and substrate specificities of antibodies exhibiting neutrophil nuclear reactivity--a methodological study.},
  author={B Bang la Cour and Allan Wiik and Mimi H\oier-Madsen and Bo Baslund},
  journal={Journal of immunological methods},
  year={1995},
  volume={187 2},
  pages={287-95}
}
In a serological laboratory with a routine service for determining autoantibodies to human neutrophils, antibodies giving a selective or preferential reaction with the nucleus or perinuclear area of neutrophils are not uncommon. The aim of this study was to look for clinical correlates with the presence of such neutrophil-reactive autoantibodies. The specificity of such antibodies for nuclear or cytoplasmic antigens was studied in 65 consecutive sera displaying nuclear/perinuclear reactivity at… CONTINUE READING

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