Clinical correlates and familial aggregation of age at onset in bipolar disorder.

@article{Lin2006ClinicalCA,
  title={Clinical correlates and familial aggregation of age at onset in bipolar disorder.},
  author={Ping-I Lin and Melvin G. McInnis and James B. Potash and Virginia L. Willour and Dean F. Mackinnon and J. Raymond Depaulo and Peter P. Zandi},
  journal={The American journal of psychiatry},
  year={2006},
  volume={163 2},
  pages={
          240-6
        }
}
OBJECTIVE To assess whether age at onset variation reflects underlying genetic heterogeneity in bipolar disorder, the authors examined the clinical and familial characteristics of age at onset in bipolar disorder subjects from families with multiple affected members. METHOD A total of 211 families with 1,856 subjects were ascertained through bipolar I disorder probands. All the subjects were assessed with the Diagnostic Interview for Genetic Studies and assigned diagnoses by trained… CONTINUE READING

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