Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system.

@article{Weinberg2009ClinicalCO,
  title={Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system.},
  author={Olga K Weinberg and Mahesh Seetharam and Li Ren and Katie Seo and Lisa N Ma and Jason Merker and Jason R. Gotlib and James L Zehnder and Daniel Alan Arber},
  journal={Blood},
  year={2009},
  volume={113 9},
  pages={1906-8}
}
Although some studies have validated the 2001 World Health Organization (WHO) classification of acute myeloid leukemia (AML), including the importance of multilineage dysplasia, others have suggested that multilineage dysplasia correlates with unfavorable cytogenetics but has no independent impact on prognosis. In 2008, the revised WHO classification has expanded this category into "AML with myelodysplasia-related changes" (AML-MRC). We evaluated the clinical, pathologic, cytogenetic, and… CONTINUE READING

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