Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.

@article{Campos2009ClinicalCO,
  title={Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.},
  author={Michael A Campos and Saleh Alazemi and Guoyan Zhang and Matthias A. Salathe and Adam Wanner and Robert A Sandhaus and Horst Baier},
  journal={Chest},
  year={2009},
  volume={135 3},
  pages={600-608}
}
BACKGROUND The clinical characteristics of elderly subjects with alpha(1)-antitrypsin deficiency (AATD)-associated COPD have not been described. METHODS The clinical, demographic, health-related quality of life (HRQoL) characteristics and 1-year exacerbation rates of 275 subjects with AATD and COPD receiving augmentation therapy aged > 59 years (mean [+/- SD] age, 66.3 +/- 5.7 years) were compared to those of 354 subjects aged 50 to 59 years (mean age, 54.3 +/- 2.8 years) and 293 subjects… CONTINUE READING
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