Clinical benefits related to the combination of ketamine with morphine for patient controlled analgesia after major abdominal surgery.

@article{Mebazaa2008ClinicalBR,
  title={Clinical benefits related to the combination of ketamine with morphine for patient controlled analgesia after major abdominal surgery.},
  author={Mhamed Sami Mebazaa and Tahar Mestiri and Boubaker Kaabi and Mohamed Salah Ben Ammar},
  journal={La Tunisie medicale},
  year={2008},
  volume={86 5},
  pages={435-40}
}
BACKGROUND combination of ketamine may improve morphine patient controlled analgesia (PCA) but clinical results are still equivocal. AIM The authors designed a powerful study to evaluate this hypothesis after major abdominal surgery. METHODS 138 patients undergoing abdominal surgery participated in the randomized double blind study. Patients were allocated to two groups: M-group: morphine 0.5 mg/ml + placebo in PCA and MK-group: morphine 0.5 mg/ml + ketamine 0.5 mg/ml with the same bolus… CONTINUE READING