Clinical benefit of 11C methionine PET imaging as a planning modality for radiosurgery of previously irradiated recurrent brain metastases.

@article{Momose2014ClinicalBO,
  title={Clinical benefit of 11C methionine PET imaging as a planning modality for radiosurgery of previously irradiated recurrent brain metastases.},
  author={Toshiya Momose and T Nariai and Takuya Kawabe and M Inaji and Yoji Tanaka and Shinya Watanabe and Taketoshi Maehara and Keiichi Oda and Kenji Ishii and Kiichi Ishiwata and Masaaki Yamamoto},
  journal={Clinical nuclear medicine},
  year={2014},
  volume={39 11},
  pages={939-43}
}
OBJECT Stereotactic radiosurgery with gamma knife (GK-SRS) generally improves the focal control of brain metastases. Yet in cases of focal recurrence at a previous radiation site, MRI is often imperfect in differentiating between active tumor and radiation injury. We have examined whether the use of C methionine (MET) with PET will facilitate this differentiation and improve the outcome of GK-SRS for focally recurrent brain metastases after prior treatment. METHODS Eighty-eight patients… CONTINUE READING