Clinical aspects and treatment of juvenile Graves' disease.

  title={Clinical aspects and treatment of juvenile Graves' disease.},
  author={Hans Perrild and Lene Daugaard Lavard and Bendt Brock-Jacobsen},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  volume={105 Suppl 4},
Thyrotoxicosis in childhood and adolescence is a rare disease most frequently due to Graves' disease, but non-autoimmune adenomatous goiters are also found. A strong correlation to HLA class II DRB1*0301 and a protective role of DRB1*0701 has been established in juvenile Graves' disease. The natural course of the disease seem to be remission in many, if enough observation time is allowed. Apart from goiter size and the severity of disease at onset, no certain prognostic factors has yet been… CONTINUE READING