Clinical approaches to preserve beta-cell function in diabetes.

@article{Wajchenberg2010ClinicalAT,
  title={Clinical approaches to preserve beta-cell function in diabetes.},
  author={Bernardo L{\'e}o Wajchenberg},
  journal={Advances in experimental medicine and biology},
  year={2010},
  volume={654},
  pages={515-35}
}
In type 2 diabetes (DM2) there is progressive deterioration in beta-cell function and mass. It was found that islet function was about 50% of normal at the time of diagnosis and reduction in beta-cell mass of about 60% at necropsy (accelerated apoptosis). Among the interventions to preserve the beta-cells, those to lead to short-term improvement of beta… CONTINUE READING