Clinical applications of quantitative acid-base chemistry.

  title={Clinical applications of quantitative acid-base chemistry.},
  author={K J Whitehair and Steve C. Haskins and Jennifer Whitehair and Peter J. Pascoe},
  journal={Journal of veterinary internal medicine},
  volume={9 1},
Stewart used physicochemical principles of aqueous solutions to develop an understanding of variables that control hydrogen ion concentration (H+) in body fluids. He proposed that H+ concentration in body fluids was determined by PCO2, strong ion difference (SID = sum of strong positive ion concentrations minus the sum of the strong anion concentrations) and the total concentration of nonvolatile weak acid (Atot) under normal circumstances. Albumin is the major weak acid in plasma and… CONTINUE READING


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