Clinical applications of melanoma genetics.

@article{Gabree2014ClinicalAO,
  title={Clinical applications of melanoma genetics.},
  author={Michele Jacobs Gabree and Devanshi Patel and Linda Rodgers},
  journal={Current treatment options in oncology},
  year={2014},
  volume={15 2},
  pages={336-50}
}
Families that have several relatives with melanoma, multiple primary melanomas in one individual, younger than average ages of melanoma onset, and/or the presence of both pancreatic cancer and melanoma may be suggestive of a hereditary melanoma syndrome and are candidates for genetic counseling and risk assessment. Genetic counseling for hereditary melanoma presents many complexities. Only a minority of hereditary melanoma cases have been attributed to a single genetic factor, CDKN2A. Both the… CONTINUE READING

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