Clinical applications of comparative genomic hybridization

  title={Clinical applications of comparative genomic hybridization},
  author={Brynn Levy and Teresa M. Dunn and Sara Kaffe and Nataline B. Kardon and Kurt Hirschhorn},
  journal={Genetics in Medicine},
Purpose: Comparative genomic hybridization (CGH) is a powerful DNA-based cytogenetic technique that allows the entire genome to be scanned for chromosomal imbalances without requiring the sample material to be mitotically active. During the past 2 years we received many requests from various medical centers around the country to use CGH to resolve the identity of aberrant chromosomal material.Methods: We report the use of CGH for the evaluation of 12 clinical postnatal cases in which… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 11 extracted citations


Publications referenced by this paper.
Showing 1-10 of 34 references

Chromosome specific comparative genome hybridization for determining the origin of intrachromosoma 1 duplications

  • DK Griffin, P SanoudouD.AdamskiE.McGiffertC.O'Brien
  • I Med Genet
  • 1998

Similar Papers

Loading similar papers…