Clinical applications of comparative genomic hybridization

@article{Levy1998ClinicalAO,
  title={Clinical applications of comparative genomic hybridization},
  author={Brynn Levy and Teresa M. Dunn and Sara Kaffe and Nataline B. Kardon and Kurt Hirschhorn},
  journal={Genetics in Medicine},
  year={1998},
  volume={1},
  pages={4-12}
}
Purpose: Comparative genomic hybridization (CGH) is a powerful DNA-based cytogenetic technique that allows the entire genome to be scanned for chromosomal imbalances without requiring the sample material to be mitotically active. During the past 2 years we received many requests from various medical centers around the country to use CGH to resolve the identity of aberrant chromosomal material.Methods: We report the use of CGH for the evaluation of 12 clinical postnatal cases in which… CONTINUE READING

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Chromosome specific comparative genome hybridization for determining the origin of intrachromosoma 1 duplications

  • DK Griffin, P SanoudouD.AdamskiE.McGiffertC.O'Brien
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